Naproxen

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Naproxen is the alpha-aryl propionic acid cousin of ibuprofen, this time hung off a 6-methoxynaphthalene instead of an isobutylbenzene. The teaching skeleton is racemic; the marketed drug is the (S)-enantiomer, but the asymmetric resolution / Noyori hydrogenation is a separate lesson. Walk the bonds back: the easiest cut undoes the carboxylic acid, then the alcohol, then the ketone, then the ether.

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Pick the bond you want to cut from the strip below the structure.

Cell id: naproxen

Pick a bond to disconnect

Use the bond strip below the structure to pick the bond you want to cut. Each chip shows the atom indices and the element pair so you can read them with a screen reader.

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