Pyrethrin I: spot the stereochemistry flaw
Single questionKey cyclopropanation in the chrysanthemic acid arm of pyrethrin I: Cu-catalyzed carbene addition of ethyl diazoacetate to 2,5-dimethyl-2,4-hexadiene. The reaction class, reagents, and conditions match. Check the relative configuration on the cyclopropane.
Cyclopropane cis vs trans diastereomers
Cu-carbene cyclopropanation stereochemistry
Chrysanthemic acid configuration
Find the flaw
Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.
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