Omeprazole: spot the conditions flaw

Single question

Final-step oxidation of the thioether to the sulfoxide on the omeprazole scaffold. The reaction class and the oxidant are right. Check the stoichiometry and the temperature.

Selective sulfide to sulfoxide oxidation

Overoxidation to sulfone with excess peroxide

Omeprazole Pyne / Sharpless processes

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.

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