Gefitinib: spot the wrong reaction class

Single question

Final aryl C-N bond formation on the gefitinib quinazoline scaffold. The aniline, the chloroquinazoline, and the conditions look right. Read the reaction class label.

SNAr vs Buchwald-Hartwig amination on activated heterocycles

When a transition-metal catalyst is unnecessary

Process chemistry purity considerations

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.

Discussion

0 comments

Loading discussion...