Skip to content

BODIPY 493/503: spot the fabricated intermediate

Single question

Three-step route to the BODIPY 493 core: pyrrole plus aldehyde condense to a dipyrromethane, oxidize, then coordinate BF2. Look carefully at the species drawn after the first condensation.

Pyrrole + aldehyde condensation to dipyrromethane
Distinguishing dipyrromethane from calix[4]pyrrole
Mechanistic plausibility of macrocyclic intermediates

Find the flaw

Click the step that contains the flaw, or pick “No flaw” if you think every step is correct.